Effect of levetiracetam in patients with epilepsy and interictal epileptiform discharges
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چکیده
منابع مشابه
Effect of levetiracetam in patients with epilepsy and interictal epileptiform discharges
The effect of acute treatment with the new antiepileptic drug (AED) levetiracetam (Keppra) on the frequency of interictal epileptiform discharges (IEDs) was evaluated in a double-blind, placebo-controlled, crossover study with therapeutic drug monitoring and serial electroencephalographic (EEG) observations. Acute (500 mg twice daily) and chronic (individualized, 500-1000 mg twice daily) doses ...
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Ictal epileptiform discharges (EDs) are characteristic signal patterns of scalp electroencephalogram (EEG) or intracranial EEG (iEEG) recorded from patients with epilepsy, which assist with the diagnosis and characterization of various types of epilepsy. The EEG signal, however, is often recorded from patients with epilepsy for a long period of time, and thus detection and identification of EDs...
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The diagnosis of epilepsy heavily depends on the detection of epileptiform discharges in interictal EEG, the EEG in between two seizures. By visual analysis a physician wants to detect these epileptiform discharges (spikes). Due to the wide variety of morphologies of epileptiform discharges, and their similarity to waves that are part of normal EEG or to artifacts, this detection is far from st...
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PURPOSE To assess the latency of interictal epileptiform discharges (IED) and seizures in long-term EEG recordings of patients with epilepsy. METHOD IED latency was measured in 210 consecutive patients (mean (SD) age 38.6 ± 13.9 years) with active epilepsy and the relationship to clinical variables was analyzed retrospectively. Median duration of EEG recording was 101.5h (95% confidence inter...
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ژورنال
عنوان ژورنال: Seizure
سال: 2001
ISSN: 1059-1311
DOI: 10.1053/seiz.2001.0582